Re: DNP LOG-FIRST TIME
Posted: Fri Apr 09, 2021 6:08 pm
While MENT maintains some moderate level of estrogenic activity, this does not appear to be the case with DMN. Studies with other 11 beta modified steroids like fluoxymesterone have shown that substitutions to this point on the steroid backbone inhibit estrogen conversion, which strongly suggests that DMN is a non-aromatizable nandrolone derivative. Furthermore, studies looking at the relative binding of this agent to the estrogen receptor have shown extremely weak binding affinity. As such, no appreciable intrinsic estrogenic activity appears to be present with this steroid. It seems reasonable to consider it a non-estrogenic drug. Similar to nandrolone and MENT, however, DMN maintains some moderate level of progestational activity. Which could mimic/intensify estrogen action in the body. This, however, is likely not going to be problematic unless high doses are taken, or the drug is administered in higher doses alongside other strongly aromatizable agent (obviously not the target clinical use for such a drug). Overall, it would appear the DMN is not only a strongly anabolic and mildly androgenic agent, but it?s also one not highly prone to causing estrogenic- type side effect such as gynecomastia, increased water retention or fat gain. Anecdotical report seem to support this conclusion as well. DMN does have one good thing going for it as far as safety is concerned. Unlike most of the recent ?designer steroids? being released, it?s not a e-17 alpha alkylated substance. Although human studies are lacking in this regard, it seems reasonable to conclude that this drug displays relatively low hepatotoxity (liver toxicity). That is usually the case with non-17-methylated steroids, although at times even some of these drugs have been shown to cause elevated liver stress if taken into high a dosage or for too long a duration. Trenbolone, nandrolone and methenolone (Primabolan) have all displayed such liver toxicity in clinical reports, albeit isolated ones. Let?s therefore, not confuse ?low toxity? with absolutely harmless. In a high enough dosage, you can likely run into trouble. The sheer potency of this drug suggest that daily doses below 1mg are going to be most commonly applied by bodybuilders. Doses well in excess of this are likewise discouraged. 17-methyllated steroids also tend to negatively affect lipids more so that their non-methylated analogs. This is one of the biggest drawbacks when it comes to the health risks of these drugs they legitimately and strongly affect a powerful factor in cardiovascular health. Without e-17 alpha methylation, DMN should have a less dramatic impact on your lipid. It?s still a potent, non estrogenic drug, however, and as such will still cause negative changes to HDL and LDL levels in most users when taken in an athletically sufficient dose. Proper monitoring of serum lipids is highly recommended with use, as would be suggested with nearly all cycles. Still, it should be better that something like winstrol or Dianabol. Overall, DMN seems to be potent and comparably less toxic new addition to the world of the underground designer steroids. One must always remember that this is a very potent drug, however, and while likely fairly safe when used responsibly, can be risky (as any steroid can) it abused.