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How safe is trenbolone?

Posted: Thu Oct 15, 2020 8:17 am
by Vision
HOW SAFE IS IT?
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How safe is trenbolone?

Thousands of bodybuilders inject themselves with trenbolone despite the fact that we know so little about the side effects of this anabolic steroid. That's why Australian researchers tested trenbolone on rats, in the hope that it has the desirable features of testosterone but not the undesirable ones. If this turns out to be the case, then trenbolone might be useful for men who produce too little testosterone.


Trenbolone
Many of the undesirable characteristics of testosterone are the work of estradiol and DHT, both products of testosterone conversion. Because trenbolone cannot convert into those metabolites, American researchers have suggested that trenbolone might be a SARM. [Steroids. 2010 Jun;75(6):377-89.] https://pubmed.ncbi.nlm.nih.gov/20138077/

According to Androgens and Anabolic Agents: Chemistry and Pharmacology by Julius Vida, trenbolone is a kind of super-nandrolone. Which means that studies where rats have been injected with trenbolone have shown that the relationship between trenbolone's androgen and anabolic qualities is similar to that of nandrolone. But both the androgenic and anabolic effect of trenbolone are considerably stronger than those of nandrolone.

The figure below comes from Androgens and Anabolic Agents.
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In 2002 American researchers compared the anabolic and androgenic effects of trenbolone with those of testosterone propionate. This study showed that trenbolone has noticeably fewer androgenic effects than testosterone propionate does. [Toxicol Sci. 2002 Dec;70(2):202-11.] https://pubmed.ncbi.nlm.nih.gov/12441365/
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Study

The Australian researchers implanted a pump in their rats, which released 2 mg trenbolone per kg bodyweight daily for six weeks. [TREN] Rats in a control group were given a pump with no active ingredients. [CTRL] The human equivalent of the dose studied is about 20-30 mg trenbolone per day.

Results
At the end of the six weeks, the trenbolone rats were lighter than the animals in the control group. They had gained lean body mass and lost a fair amount of fat mass.
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The trenbolone rats' prostate however had become 49 percent larger than that of the rats in the control group. That sounds serious so the researchers examined the organ in minute detail. They found no inflammation or cancer cells.

This is probably because trenbolone reduced the estradiol level. Trenbolone also had the same effect on the rats' testosterone level. Trenbolone had almost no effect on dimensions or structure of the testes, unlike the effects seen when testosterone is administered to rats in studies.

Trenbolone increased the rats' insulin sensitivity - and therefore reduced the HOMA-IR. This is probably a result of the effect on body composition.

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The level of triglycerides and LDL in the rats' blood went down, which is a desirable effect. The HDL level decreased too, however, which is an undesirable effect.

The researchers detected no effects on liver enzymes. So in the dose tested, trenbolone is not dangerous for the liver.

Conclusion
"Further investigation into the comparative benefits conferred by trenbolone therapy relative to the current gold standard, testosterone, are well justified by these findings", the researchers conclude. "Particularly in relevant models of obesity and metabolic dysregulation."

Source:
Steroids. 2015 Feb;94:60-9. https://pubmed.ncbi.nlm.nih.gov/25554582/

Re: How safe is trenbolone?

Posted: Fri Oct 23, 2020 12:05 pm
by MONSTRO
Why people talk so bad about trenbolone and is side effects . Here we have some good news , he had sides but alot good thinks to.
And if he improves my insulin sensativity i will use all year round with slin and get HUGE :lol: :lol: :lol:

Re: How safe is trenbolone?

Posted: Sat Oct 31, 2020 6:04 am
by HFO3
what an interesting article. I get great results from 200 mgs of tren, its nothing ike 300 but still very effective. is anyone running tren?

Re: How safe is trenbolone?

Posted: Wed Nov 30, 2022 4:18 am
by MONSTRO
Now im not running but i use almost all year round ( sounds crazy ) , but when i dont have real good HGH like now i use trenbolone to never get fat , its the best shit to have real results

Re: How safe is trenbolone?

Posted: Wed Nov 30, 2022 4:32 am
by Vision
MONSTRO wrote: Wed Nov 30, 2022 4:18 am Now im not running but i use almost all year round ( sounds crazy ) , but when i dont have real good HGH like now i use trenbolone to never get fat , its the best shit to have real results
:ymhug:
Our brutha, great to see you man.. Yes I recall you running it for a while, you always did well with it. What was your favorite compound that you ran for LONG periods on end, like no break, same dose for LONG TIME?

Re: How safe is trenbolone?

Posted: Tue Apr 11, 2023 7:29 am
by Mobster
Sweep the leg! :))

Re: How safe is trenbolone?

Posted: Fri Apr 14, 2023 10:08 pm
by Hany-Support
Everything is for people in the right dose.

With Trenbolone, most people overdo it. It's not fun.

How to take it at the end of reduction.

Honestly, if you do it only as a hobby, in my opinion, it's better not to use it.

And if you insist, probiotics, enzymes, plenty of water, and liver protection are essential.

Re: How safe is trenbolone?

Posted: Sat Apr 15, 2023 8:50 am
by Mobster
Tren, for elderly men with medical issues, was shown to have dementia like side effects on their brains. This will be at lower than PED doses

Re: How safe is trenbolone?

Posted: Mon Apr 17, 2023 7:32 am
by Hany-Support
Mobster wrote: Sat Apr 15, 2023 8:50 am Tren, for elderly men with medical issues, was shown to have dementia like side effects on their brains. This will be at lower than PED doses
Trenbolone, this is one great strong agent .. It's good that you mention it, if someone insists on Tren, it's definitely worth using the RAD140 peptide, which has a neuroprotective effect

Re: How safe is trenbolone?

Posted: Mon May 15, 2023 6:05 pm
by Push50
Hany-Support wrote: Mon Apr 17, 2023 7:32 am
Mobster wrote: Sat Apr 15, 2023 8:50 am Tren, for elderly men with medical issues, was shown to have dementia like side effects on their brains. This will be at lower than PED doses
Trenbolone, this is one great strong agent .. It's good that you mention it, if someone insists on Tren, it's definitely worth using the RAD140 peptide, which has a neuroprotective effect
So, what age are you referring to? @Mobster