How safe is trenbolone?

[berlin]

HOW SAFE IS IT?

How safe is trenbolone?

Thousands of bodybuilders inject themselves with trenbolone despite the fact that we know so little about the side effects of this anabolic steroid. That's why Australian researchers tested trenbolone on rats, in the hope that it has the desirable features of testosterone but not the undesirable ones. If this turns out to be the case, then trenbolone might be useful for men who produce too little testosterone.


Trenbolone
Many of the undesirable characteristics of testosterone are the work of estradiol and DHT, both products of testosterone conversion. Because trenbolone cannot convert into those metabolites, American researchers have suggested that trenbolone might be a SARM. [Steroids. 2010 Jun;75(6):377-89.] https://pubmed.ncbi.nlm.nih.gov/20138077/

According to Androgens and Anabolic Agents: Chemistry and Pharmacology by Julius Vida, trenbolone is a kind of super-nandrolone. Which means that studies where rats have been injected with trenbolone have shown that the relationship between trenbolone's androgen and anabolic qualities is similar to that of nandrolone. But both the androgenic and anabolic effect of trenbolone are considerably stronger than those of nandrolone.

The figure below comes from Androgens and Anabolic Agents.

In 2002 American researchers compared the anabolic and androgenic effects of trenbolone with those of testosterone propionate. This study showed that trenbolone has noticeably fewer androgenic effects than testosterone propionate does. [Toxicol Sci. 2002 Dec;70(2):202-11.] https://pubmed.ncbi.nlm.nih.gov/12441365/

Study

The Australian researchers implanted a pump in their rats, which released 2 mg trenbolone per kg bodyweight daily for six weeks. [TREN] Rats in a control group were given a pump with no active ingredients. [CTRL] The human equivalent of the dose studied is about 20-30 mg trenbolone per day.

Results
At the end of the six weeks, the trenbolone rats were lighter than the animals in the control group. They had gained lean body mass and lost a fair amount of fat mass.



The trenbolone rats' prostate however had become 49 percent larger than that of the rats in the control group. That sounds serious so the researchers examined the organ in minute detail. They found no inflammation or cancer cells.

This is probably because trenbolone reduced the estradiol level. Trenbolone also had the same effect on the rats' testosterone level. Trenbolone had almost no effect on dimensions or structure of the testes, unlike the effects seen when testosterone is administered to rats in studies.

Trenbolone increased the rats' insulin sensitivity - and therefore reduced the HOMA-IR. This is probably a result of the effect on body composition.


The level of triglycerides and LDL in the rats' blood went down, which is a desirable effect. The HDL level decreased too, however, which is an undesirable effect.

The researchers detected no effects on liver enzymes. So in the dose tested, trenbolone is not dangerous for the liver.

Conclusion
"Further investigation into the comparative benefits conferred by trenbolone therapy relative to the current gold standard, testosterone, are well justified by these findings", the researchers conclude. "Particularly in relevant models of obesity and metabolic dysregulation."

Source:
Steroids. 2015 Feb;94:60-9. https://pubmed.ncbi.nlm.nih.gov/25554582/
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As a bodybuilder, safety is paramount in our pursuit of physical excellence. Trenbolone is a powerful anabolic steroid used by some for its muscle-building effects. While it can deliver remarkable results, it's essential to recognize its potential risks. Trenbolone is known to have more severe side effects compared to other steroids, such as cardiovascular issues and psychological effects.

Ensuring safety involves proper dosage, understanding your body's response, and regular health check-ups. It's crucial to consult with a healthcare professional before considering any steroid use to weigh the potential benefits against the risks and explore safer alternatives. Ultimately, our health should always be a top priority in our bodybuilding journey.

[hammer2204]

This study shows that it's not as scary as it seems. But I would like to say that it's worth considering finding an individual dosage. Its anabolic effect is three times stronger than testosterone. So, there are options for finding the right dose.

[MONSTER]

Steroids are medications , quimicals, so all of them are not healthy for you. And you should thinking alot before starting any protocol / cycle because when you come in you never go out .
In my opinion since i do this because i chose to it and achive my dream body i prefer to use what works , and what works amazing is:
TRENBOLONE
TEST
HGH
INSULIN
IGF
SUPERDROL
M1T

I prefer to use less amount of something that works than using 1gr or more of primo and have less ythan half results of 300mg tren

If i have only 2 drugs tom use i will chose Test + trenbolone anytime

[William]

According to recent studies, Turinabol does not cause as serious side effects as commonly believed. Nevertheless, everyone should be careful and monitor their condition closely. As practice shows, there is no universal dosage. The optimal dosage can vary greatly depending on many factors, such as age, weight, level of physical activity and individual characteristics of the body.